Fun fact : I broke Captain Mareth
Context : as I had left the Protectorate questline aside during the main game I decided to go through to garner a few more XPs. After having slaughtered the free drones in their base but before using the mutagen container I came back around and decided to play with Dess, that murdering psycho. Since we were in an uncontrolled zone (right before drone base entrance) I set up a trap and killed her. Got the rubber glove oddity for my trouble. Then, after completing the mission, I returned to Ft Apogee. Mareth congratulated me then talk to Dess... who answered ! Except the portrait was missing from her dialogue window.
So on one hand the game acknowledged she was dead, but it wasn't flagged or anything.
Also : it's possible to kill Void the same way.
I know you're busy with the expansion but I just thought I'd make a mention of it anyway.
Good day.