First big problem: Str is too low, almost any sledg build should aim for 14-16 strength anyway and on dominating difficulty you would loose your biggest advantage of dealing damage in large spikes if you don't have max Str, which is unacceptable on this difficulty.
Second big problem: no stealth. You can't win dominating without stealth. Enemies hit hard and there are lot more of them. Even if at some point you get best super steel armor, psi enemies can still ignore it and there is at least one unavoidable fight with a LOT of them. Without stealth you just die even with all that hp and Thick Skull. You can be a heavy sledg, but you still need stealth and some stealthy clothes to use on such occasions.
Third problem: No Cheap Shot and Expose Weakness. Boi, you are in trouble. Those a must have for any melee characters. First one gives you 50% crit damage and without it your Critical Power feat is absolutely pointless, since you gonna have only base 100% crit damage bonus unless you wield tungsten sledg. Expose Weakness is a must because mechanical damage is the most resistant damage on this game and it's your only way of mitigating this. There are plenty of enemies with heavy mech resist (like bladelings, bots and so on) and you will have a very hard time killing them without this feat.
Small stuff: Bone breaker is mostly pointless. Even on dominating your crits will kill most of the enemies (with critical power and chep shots) or at least leave them with little health, so 25% increase in damage will not be useful 99% of the time. And enemies that have this much health often are immune to this debuff since it works only on targets that have ribs (so, no robots for example). There are exceptions on dominating difficulty where it can be useful, like a couple of human boss characters (Carnifex springs to mind), but it still is a VERY situational feat. Taste for Blood on the other hand is much more useful since you get buff, instead of giving debuff to the enemy, and you get one stack of it for every enemy you kill. In battles with lots of enemies it's not hard to get constant +50% damage buff on your character.
Yell can be actually useful since it's less known effect is getting affected enemies out of stealth. Probably not an intentional effect, but a very useful one, since it has a pretty big radius. You can get crawlers/gaunts/stalkers out of stealth with it much easier than with flares.
No Armor Sloping is a problem, since even with Sprint and Hit and Run (btw gains from Hit and Run are affected by armor penalty iirc) you gonna move like drunk tortoise if you want to get yourself good metal armor.
Here is a character that i finished the game on dominating with, if you want some reference
http://underrail.info.tm/build/?GRAGBgYDAwYAAADChwAARmdXADLCgGQAcG4AAABpAFAABg4SJCgtMTk8RUtQVAP.S. Sorry for misspelling and typos. It's late and i'm slightly drunk and too lazy to check the text twice.