Just played through for the fourth time (this last time on hard), so I obviously love the game. I'd like to suggest a few interface tweaks that would, in my opinion, improve the player's quality of life. I would suspect that some players would find these suggestions quite trivial, but in my mind they are little things that are annoying.
1. The ability to be able to sort inventory items by weight, be that the entire inventory or just the inventory category one is interested in;
2. The ability to filter the inventory, much like you already do with the "feats" and "specialization" lists;
3. Move the inventory tab on the far right (Inventory minus quest items) to the on the far left of the inventory tabs as the default tab. I find that when I pull up the inventory, the first thing I do is click on the (inventory minus quest items tab) because I rarely need to look at the quest items and the quest items can take up a lot of space;
4. I find there is too much mouse movement when crafting, especially when your doing something repetitious, such as "recycle item": you have to keep moving your mouse from the inventory window to the "Create" button and back. Would love it if the player could bind a key to the "create" button. That is, the player could then stop moving the mouse so far by double-clicking on the item in the inventory then pressing the key bound to the "Create" button.
For the sake of context, I'm almost 60 and am starting to find precise mouse work a little harder these days... Absolutely love the game!