Cryo gas and chem pistols can freeze enemies solid, which renders them not merely immobile but actionless. It's potentially valuable when you're fighting heavy hitting melee. Incap with a flashbang or something then let them sit in the cold for two turns, stacking the movement debuff and eventually freezing solid. I believe they can also be shattered that way (been a while, sorry, and I don't trust my memory enough to be certain), and shattering can be done with less than lethal damage, so high-health enemies can be killed more rapidly since you don't have to get them to 0 health to kill them.
It's kind of niche, but I don't think it's without use.