A number of good points have been raised, some twice.
Yes, there definitely needs to be warnings for touching gear. Right now, there's too much setting-the-whole-town against you for accidentally touching a table.
There are characters like the guard at the SGS caves gate, where you try to click them but accidentally hit the door/fence they are behind, which triggers hostility. I know a warning dialog may have been added since the initial release, but benign conversations are positioned right next to 'untouchable' tables and gear even in SGS, Camp Hathor, etc...
In a pixel-based game, this is very frustrating, and has led me to have to restore saved games more than once. There needs to be more escalation, and a less binary approach towards touching stuff that is right beside a store NPC.
In real life, your character wouldn't be stupid enough to accidentally touch a 'forbidden' table or gate when trying to address a salesman or guard, I would think.
The firearms system could have suppressors applied to all calibres, although it would reduce damage and range, and probably increase wear significantly.
It would be interesting to see caltrops and bear traps made from other metals, although not really necessary.
Good points, Olnarrosh . I often found myself in the middle of one of those giant, time-consuming quests (like the Foundry quests), and forgetting what I was supposed to be doing. Who wanted the murder investigation done? Where was I supposed to look / deliver evidence?
And it would be better to be able to generate your own face somehow. Even a 3D program resulting in a 2D image would be fine. Or a "Mr. Potato Head" type system.
Lots of people have gripes about the commerce system. I find that Underrail takes a 'half-measures' approach, in that there is a more realistic system [vendors only want certain things and sell certain things at any given time], but there are none of the in-universe systems that would naturally spring up in response.
Why isn't there a system where you can consult your PDA and find out what is being sold in Core City, while you are in Camp Hathor? Is there no rudimentary intranet/BBS system in Underrail? No special service offered by people like Blaine or Oculus monitoring what's in stores?
Why can't you contact stores and reserve items? Why isn't there a courier service, as others have mentioned?
And inventory sorting-by-weight/value/etc... would greatly help with management.
Speaking of your PDA / UI, it would be nice to have a database of creatures, as mentioned. Other games have it too, it could have entries added either when you first encounter a creature, or hear about it from someone, with more datapoints being added from subsequent conversations and encounters. But if that's too much work, a straight-up database with information about strengths/weaknesses from basically the Wiki would be okay.
Regarding resolution, I have a 1920x1200 monitor, but I play the game on 1680x1050. It works okay, although it might be even better on a slightly-lower resolution (I'd have to hack my card to enable it).
I think pixel-doubling / tripling / quadrupling might be handy, given the growing prevalence of HIDPI resolutions, especially for laptops.
Zoom might work with the existing setup, I don't know.
If the game engine were 3D, from an isometric perspective, then it would be easy to deal with the resolution issue, character models, and having clothing show up on players. But that would require a brand new engine.