played on Normal 2 times, Hard 2 times, and now the 5th playthrough is on Dominating.
depending on your INT, i often left my INT at 7, with that, 100 crafting skill will get me around 125 effective crafting skill (without buffs).
and 125 effective skill will go up to 160+ with full buffs (crafting stations+hypercerebrix).
but that 160+ in skill mostly can only craft something with 130-140 material qualities, and honestly i haven't found a material that exceeds 151, which was the highest i can get (my skills wasn't enough, though), according to the wiki, the cap is 160.
i think it's still somewhat in balance, high attack skills will compensate low quality crafted weapons, while high quality crafted weapons will compensate your low attacking skills. so you can choose either one.
my tip is, don't bother increasing the crafting skills at least until mid-game onwards, because you can still find great unique weapons. approaching the late-game portion, you would most likely won't need anymore increase in Hacking, Lockpicking, etc. so you can dump the points you get into crafting skills. in late-game, you will start to get high quality materials to make equipments that are way better than the unique ones.